Development of a biosensor assessing SARS-CoV-2 main protease proteolytic activity in living cells for antiviral drugs screening.

Virologica Sinica(2022)

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摘要
•The biosensor reported in our study can monitor SARS-CoV-2 Mpro activity in living cells instead of in vitro solutions.•The biosensor reported in our study is sensitive and easy to operate.•It is suitable for high-throughput screening.•It has the potential to be used in small animal models.
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