Micro topographical instruction of bacterial attachment, biofilm formation and in vivo host response

1 National Biofilms Innovation Centre, Biodiscovery Institute and School of Life Sciences, University of Nottingham, Nottingham, United Kingdom. 2 School of Computer Science, University of Nottingham, Nottingham United Kingdom Advanced Materials and Healthcare Technologies Division, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom. Laboratory for Cell Biology-Inspired Tissue Engineering, MERLN Institute for TechnologyInspired Regenerative Medicine, Maastricht University, Maastricht, the Netherlands. BioInterface Science lab, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, the Netherlands. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Kingsbury Drive, Melbourne, Victoria 3086, Australia and Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia CSIRO, Pullenvale, Australia, Immunology & Immuno-bioengineering Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.