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Comorbidities of depression in men and women: a UK biobank based study

European Neuropsychopharmacology(2021)

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Abstract
Largest, single-centre study of clinical and functional outcomes of patients who underwent endoprosthetic replacement (EPR) for aggressive distal tibial bone tumours.Retrospective observational study of eight patients was undertaken.Median follow-up was 77 months (range 13–276). Cumulative five and ten year survival was 63% and 42% respectively. Three patients developed either disease recurrence or metastases post-surgery. One patient developed deep infection requiring washout and suppressive antibiotics. No patients required revision surgery. The median MSTS score at last follow up was 66%.EPR of the distal tibia is a viable option and provides good function outcomes.
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Cost-effectiveness Analysis
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