Protein expression by immunohistochemistry is associated with CCNE1 and BRD4 gene amplification

Gynecologic Oncology(2022)

引用 0|浏览2
暂无评分
摘要
In high grade serous ovarian cancer (HGSOC), co-amplification of CCNE1 and bromodomain and extraterminal 4 (BRD4) genes is associated with poor overall survival. Our objective was to determine if protein expression by immunohistochemistry can be used as a surrogate marker for CCNE1 and BRD4 amplification measured by fluorescent in situ hybridization (FISH).
更多
查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要