GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma.

Wenliang Tan,Kelin Zhang,Xinming Chen,Lei Yang,Sicong Zhu,Yingcheng Wei,Zhiqin Xie,Yajin Chen,Changzhen Shang

Journal of advanced research（2023）

引用 6|浏览10

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摘要

Our findings indicated that GPX2 plays an important role in lenvatinib-induced HCC cell apoptosis, which might serve as a biomarker for instruction of lenvatinib therapy in HCC patients.

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关键词

Apoptosis,GPX2,Hepatocellular carcinoma,Lenvatinib,ROS

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