T-cell clonality assessment by flow cytometry using anti-TCR-Cβ-1: A tertiary hospital experience

Chow Yee Lai,Malgorzata Gorniak,Sue Morgan,George Grigoriadis, Giles Kelsey,Shaun Fleming

Pathology（2022）

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摘要

Background: The recent discovery of a monoclonal antibody specific for TCR-Cβ-1 (encoded by TCRCB1) heralded a new method for αβ-T-cell clonality assessment by flow cytometry. Each αβ-T-cell contains a β-chain constant region encoded by either TCRCB1 or TCRCB2.1

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