Exploiting CD22 on Memory B Cells to Induce Tolerance to Peanut Allergens

The Journal of Allergy and Clinical Immunology(2022)

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摘要
Allergic reactions to peanut mediated by circulating IgE are propagated by sustained memory B cell responses. We sought to determine whether targeting mouse and human CD22 on peanut-specific memory B cells could induce tolerance to peanut allergens.
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