A Single Dose of BNT162b2 Messenger RNA Vaccine Induces Airway Immunity in Severe Acute Respiratory Syndrome Coronavirus 2 Naive and Recovered Coronavirus Disease 2019 Subjects.

Emanuela Martinuzzi,Jonathan Benzaquen,Olivier Guerin,Sylvie Leroy,Thomas Simon,Marius Ilie,Véronique Hofman,Maryline Allegra,Virginie Tanga,Emeline Michel,Jacques Boutros,Charlotte Maniel,Antoine Sicard,Nicolas Glaichenhaus,Cecil Czerkinsky,Philippe Blancou,Paul Hofman,Charles H Marquette

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2022）

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摘要

Mucosal immune response to the SARS-CoV-2 Spike protein is higher in RCSs after a single vaccine dose compared with SARS-CoV-2-naive subjects after 2 doses.

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关键词

COVID-19 mRNA vaccine,SARS-CoV-2,mucosal immunity,secretory antibodies

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