BnVIR: bridging the genotype-phenotype gap to accelerate mining of candidate variations for traits in Brassica napus

Genetic variations, which range from single nucleotide polymorphisms (SNPs) and short insertion/deletions (InDels) to large-scale structural variations (SVs), are the basis of phenotypic diversity. Understanding the effect of genetic variations on traits is critical for uncovering the genetic architecture of various phenotypes. In humans, great efforts have been made to catalog the huge amounts of variations in a single locus and their functional and phenotypic impacts, as well as detect the genetic interactions between loci underlying complex diseases, which are of great significance for pathologic studies (Li et al., 2013; Civelek and Lusis, 2014; Karczewski et al., 2020).