Dietary olive oil intake aggravates psoriatic skin inflammation in mice via Nrf2 activation and polyunsaturated fatty acid imbalance

•We investigated effects of oral olive oil administration on psoriasiform skin inflammation.•Olive oil aggravated the thickening of psoriatic skin lesions in mouse.•Olive oil overexpressed Nrf2 levels in psoriatic skin lesions of mouse.•Olive oil imbalanced the levels of oleic and linoleic acid in psoriatic skin lesions.