Thiazide use and skeletal microstructure: Results from a multi-ethnic study

•Thiazide users and non users were compared with high resolution peripheral quantitative computed tomography (HR-pQCT) and other imaging.•ArealBMD at the 1/3-radius was higher in female thiazide users versus non-users.•By HR-pQCT, adjusted mean cortical vBMD was 2.4% higher at the radius in female users versus non-users.•The effect on cortical bone may offer skeletal benefits in women taking thiazides for non-skeletal indications.