Antibacterial activity of stannate M 2 SnO 4 (M = Co, Cu, Mg, Ni and Zn) nanoparticles prepared by hydrothermal

In the present work, stannate nanoparticles M 2 SnO 4 (M = Co, Cu, Mg, Ni and Zn) were synthetized using hydrothermal technique. The structural and morphological properties of the synthetized nanoparticles have been analyzed by means of X-ray diffraction (XRD) and high-resolution transmission microscopy (HRTEM). The antibacterial activity of these stannate has been investigated using the agar well diffusion technique. The structural analysis results reveal the monocrystalline nature of the prepared nanoparticles and the presence of SnO 2 as secondary phase beside a small amount of metallic oxide. The antibacterial activity of the synthetized stannate nanoparticles was tested against a Gram-negative and Gram-positive bacteria. The results showed that all stannate nanoparticles except Mg stannate exhibit an activation against both Gram-positive and Gram-negative bacteria. The Cu and Zn stannate demonstrated higher antibacterial activity by comparison to the other stannate suggesting their potential candidature for the antibacterial activity and their utilization to develop a new antibacterial agent. A correlation between the antibacterial activity and the nanoparticle crystallite size is addressed. We concluded that a crystallite size of 12 nm seems to be an optimal size for efficient antibacterial activity of the stannate nanoparticles.