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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma with Respiratory Comorbidities: Results from the Phase 3 NAVIGATOR Study

ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology(2022)

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摘要
Tezepelumab is a human monoclonal antibody that targets thymic stromal lymphopoietin (TSLP). The phase 3 NAVIGATOR study (NCT03347279) investigated the efficacy and safety of tezepelumab in adults and adolescents with severe, uncontrolled asthma. This post hoc analysis evaluated the efficacy of tezepelumab in patients from NAVIGATOR with specific respiratory comorbidities of interest.
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