Concise Synthesis of Procyanidin B2 3,3 ''-Digallate Using Yb(OTf)(3)-Mediated Self-Condensation
SYNLETT(2022)
摘要
Lewis acid mediated self-condensation of epicatechin gallate derivative was examined. We found that Yb(OTf)(3) afforded good yield of the dimeric epicatechin gallate derivative. The condensed product was applied to the synthesis of procyanidin B2 3,3 ''-digallate.
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关键词
procyanidin, Lewis acid, condensation, epicatechin gallate, natural products
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