Pluripotency transcription factor levels in sheep embryos correlate with mRNA regulatory elements

Pabola S. Nascimento,Marcelo T. Moura,Roberta L. Oliveira-Silva,Pamela Ramos-Deus,Claudio C. Bartolomeu,Ana M. Benko-Iseppon,Jose C. Ferreira-Silva, Antonio S. Santos Filho,Marcos A. L. Oliveira

Livestock Science（2022）

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摘要

•Pluripotency genes have dynamic mRNA levels during sheep early embryogenesis.•Gene expression patterns of pluripotency genes correlate with mRNA 3′UTR elements.•RNA methylation scores correlate with pluripotency gene levels in sheep embryos.

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关键词

Embryology,LRH-1,Ovine,Ronin,Transcriptional regulator,ZFP281

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