Europium Oxide Decorated on Graphitic Carbon Nitride as Electrochemical Sensor for Ultra-Selective Enhanced Electrocatalytic Detection of Azathioprine

The purpose of this article is to describe an effective and accurate electrochemical sensor based on Europium oxide (Eu-O)/graphitic carbon nitride (g-CN) nanocomposite towards the sensing and determination of the autoimmune depressive drug Azathioprine (AZP). EuO/g-CN nanocomposite was produced by using a superficial sonochemical technique. As demonstrated by impedance measurements, g-CN to the EuO lattice considerably low resisting property, which is advantageous for the electrochemical sensing process. Due to the unique aggregated coral like EuO nanoparticle on the flake-like g-CN, it shows excellent synergy and the electrode modified with EuO/g-CN demonstrated outstanding electrochemical behaviour for AZP sensing. The electrode modified with EuO/g-CN exhibited high sensitivity (0.410 mu A mu M-1 cm(-2)) and a detectable limit (8 nM), with high selectivity toward AZP. To demonstrate the sensor's utility, it was used to detect AZP in real sample, the determination of AZP was exhibited in biological fluids namely, human blood serum and urine samples.