Lexical-semantic system disruption correlation with Alzheimer's pathophysiological processes

Semantic cognition is early affected in Alzheimer's disease (AD), but its relationship with AD neuropathological hallmarks burden (i.e. amyloidosis, A; tauopathy, T; neurodegeneration, N) is controversial. We addressed this issue investigating the relationship between non-traditional semantic neurolinguistic metrics and AD pathology.