The role of concomitant chemoradiotherapy versus radiation alone in T1-3N0 HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma

Oral Oncology(2022)

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摘要
•Definitive RT is sufficient for T1-T2N0 OPSCC. Concurrent CRT is not recommended.•T3N0 OPSCC should be treated with concurrent chemoradiation irrespective of p16 status.•p16-positive T3N0 should be considered for clinical trials evaluating de-escalation.
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关键词
Oropharyngeal squamous cell carcinoma,Concurrent chemoradiation,Radiation alone,T3N0,HPV positive,HPV negative,NCDB,National cancer database
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