Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Neutralization After Antenatal Messenger RNA Vaccination.

Amihai Rottenstreich,Olesya Vorontsov,Or Alfi,Gila Zarbiv,Esther Oiknine-Djian,Roy Zigron,Geffen Kleinstern,Michal Mandelboim,Shay Porat,Dana G Wolf

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2022）

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摘要

We evaluated the neutralization efficiency against SARS-CoV-2 Omicron variant in maternal and cord blood sera after antenatal BNT162b2 vaccination. Neutralizing antibodies against Omicron were lacking at the time of delivery after 2-dose vaccination. A third booster dose was essential in building neutralizing antibody capacity against Omicron among mothers and neonates.

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COVID-19,Omicron,SARS-CoV-2,pregnancy,vaccination

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