Cortical excitatory and inhibitory correlates of the fronto-limbic circuit in major depression and differential effects of left frontal brain stimulation in a randomized sham-controlled trial

Cheng-Ta Li,Chi-Hung Juan,Hui-Ching Lin,Chih-Ming Cheng,Hui-Ting Wu,Bang-Hung Yang,Shih-Jen Tsai,Tung-Ping Su,Paul B. Fitzgerald

Journal of Affective Disorders（2022）

引用 9|浏览3

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摘要

•Underlying molecular mechanisms of fronto-limbic circuit involved glutamatergic excitation and GABAergic inhibition.•rTMS mainly modulated glutamatergic neurotransmission at left prefrontal cortex.•Mechanisms of iTBS might involve GABA-B receptor mediated inhibition.

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关键词

Depression,Repetitive transcranial magnetic stimulation,Theta burst stimulation,GABA,Glutamate

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