Spatiotemporal responses of trabecular and cortical bone to complete spinal cord injury in skeletally mature rats

Jonathan A Williams,Carmen Huesa,James F C Windmill,Mariel Purcell,Stuart Reid,Sylvie Coupaud,John S Riddell

Bone Reports（2022）

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摘要

•Skeletally mature spinal cord transected rats display biphasic bone loss•The osteoporosis manifests over slower time scales than in skeletally immature rats.•Relevancy for testing efficacy of interventions against SCI-induced osteoporosis.

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关键词

Spinal cord injury,Skeletally mature,Osteoporosis,microCT,Bone morphometry,Mechanical testing

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