Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study

Magnus Lindskog,Anna Laurell,Anders Kjellman,Bohuslav Melichar,Pablo Maroto Rey,Henryk Zieliński,Felipe Villacampa,Pierre Bigot,Bajory Zoltan,Omi Parikh, David Vazquez Alba, Åsa Jellvert,Tibor Flaskó,Enrique Gallardo,Maria José Ribal Caparrós,Gunta Purkalne, Peter Suenaert,Alex Karlsson-Parra,Börje Ljungberg

European Urology Open Science（2022）

引用 3|浏览20

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摘要

Intratumoral injection of ilixadencel, consisting of proinflammatory allogeneic dendritic cells, before nephrectomy, followed by sunitinib treatment after nephrectomy showed a trend for improved tumor response rate and overall survival, compared with sunitinib monotherapy.

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关键词

Allogeneic dendritic cells,Ilixadencel,Intratumoral administration,Metastatic renal cell carcinoma,Off the shelf,Phase 2 trial,Randomized,Sunitinib

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