Characterization of the DNA Binding Domain of StbA, A Key Protein of A New Type of DNA Segregation System

Valentin Quèbre,Irene Del Campo,Ana Cuevas,Patricia Siguier,Jérôme Rech, Phan Thai Nguyen Le,Bao Ton-Hoang,François Cornet,Jean-Yves Bouet,Gabriel Moncalian,Fernando de la Cruz,Catherine Guynet

Journal of Molecular Biology（2022）

引用 3|浏览5

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摘要

•The N-ter DNA binding domain of StbA is structurally related to the PadR regulators.•The C-terminal domain of StbA is required for both segregation and conjugation.•Plasmid R388 conjugation depends on its subcellular positioning.

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关键词

plasmid,DNA segregation,bacterial conjugation,transcription factor,helix-turn-helix

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