Deceased donor liver transplantation in patients on direct oral anticoagulants at the time of transplant surgery: A case series

LIVER TRANSPLANTATION(2022)

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Liver TransplantationVolume 28, Issue 10 p. 1681-1684 BRIEF REPORT Deceased donor liver transplantation in patients on direct oral anticoagulants at the time of transplant surgery: A case series David M. Salerno, Corresponding Author David M. Salerno [email protected] Department of Pharmacy, NewYork-Presbyterian Hospital, New York, New York, USA Correspondence David M. Salerno, Department of Pharmacy, NewYork-Presbyterian Hospital, 525 E. 68th Street, Room K-04, New York, NY 10065, USA. Email: [email protected]Search for more papers by this authorGrace S. Lee-Riddle, Grace S. Lee-Riddle Department of Surgery, Columbia University Irving Medical Center, New York, New York, USASearch for more papers by this authorSeema Brar, Seema Brar Department of Anesthesiology, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorBenjamin Samstein, Benjamin Samstein Department of Surgery, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorRobert S. Brown, Jr., Robert S. Brown, Jr. Department of Medicine, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorChristine Lennon, Christine Lennon Department of Anesthesiology, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this author David M. Salerno, Corresponding Author David M. Salerno [email protected] Department of Pharmacy, NewYork-Presbyterian Hospital, New York, New York, USA Correspondence David M. Salerno, Department of Pharmacy, NewYork-Presbyterian Hospital, 525 E. 68th Street, Room K-04, New York, NY 10065, USA. Email: [email protected]Search for more papers by this authorGrace S. Lee-Riddle, Grace S. Lee-Riddle Department of Surgery, Columbia University Irving Medical Center, New York, New York, USASearch for more papers by this authorSeema Brar, Seema Brar Department of Anesthesiology, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorBenjamin Samstein, Benjamin Samstein Department of Surgery, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorRobert S. Brown, Jr., Robert S. Brown, Jr. Department of Medicine, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this authorChristine Lennon, Christine Lennon Department of Anesthesiology, Weill Cornell Medical Center, New York, New York, USASearch for more papers by this author First published: 03 June 2022 https://doi.org/10.1002/lt.26521Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1Salerno DM, Tsapepas D, Papachristos A, Chang JH, Martin S, Hardy MA, et al. Direct oral anticoagulant considerations in solid organ transplantation: a review. Clin Transplant. 2017; 31:12873. 2Lichvar AB, Pierce DR, Salerno D, Klem P, Waldman G, Park JM. Utilization of direct-acting oral anticoagulation in solid organ transplant patients: a national survey of institutional practices. Clin Transplant. 2020; 34:e13853. 3Douketis JD, Spyropoulos AC, Duncan J, Carrier M, le Gal G, Tafur AJ, et al. Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant. JAMA Intern Med. 2019; 179: 1469–78. 4Tomaselli GF, Mahaffey KW, Cuker A, Dobesh PP, Doherty JU, Eikelboom JW, et al. 2020 ACC expert consensus decision pathway on management of bleeding in patients on oral anticoagulants: a report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2020; 76: 594–622. 5Garcia D, Alexander JH, Wallentin L, Wojdyla DM, Thomas L, Hanna M, et al. Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures. Blood 2014; 124: 3692–8. 6Birnie DH, Healey JS, Wells GA, Ayala-Paredes F, Coutu B, Sumner GL, et al. Continued vs. interrupted direct oral anticoagulants at the time of device surgery, in patients with moderate to high risk of arterial thrombo-embolic events (BRUISE CONTROL-2). Eur Heart J. 2018; 39: 3973–9. 7Renner TA, Zalunardo MP, Weder W, Spahn DR. Bilateral lung transplantation in a patient receiving rivaroxaban anticoagulation. J Cardiothorac Vasc Anesth. 2015; 29: 723–6. 8Lange NW, Lee JH, Liu EC, Hedvat J, Weiner J, Sultan S. Deceased donor renal transplantation in patients on apixaban at time of transplant surgery: a case series. Clin Transplant. 2021; 35:e14148. 9Martinez S, Garcia I, Ruiz A, Tàssies D, Reverter JC, Colmenero J, et al. Is antivitamin K reversal required in patients with cirrhosis undergoing liver transplantation? Transfusion. 2021; 61: 3008–16. 10Intagliata NM, Maitland H, Pellitier S, Caldwell SH. Reversal of direct oral anticoagulants for liver transplantation in cirrhosis: a step forward. Liver Transpl. 2017; 23: 396–7. 11Bezinover D, Dirkmann D, Findlay J, Guta C, Hartmann M, Nicolau-Raducu R, et al. Perioperative coagulation management in liver transplant recipients. Transplantation. 2018; 102: 578–92. 12Makhoul T, Kelly G, Kersten B, Nadler M, Zammit CG, Jones CMC, et al. Incidence of thromboembolic events following administration of four-factor prothrombin complex concentrate (4F-PCC) for oral anticoagulation reversal. Thromb Res. 2020; 10(194): 158–64. Volume28, Issue10October 2022Pages 1681-1684 ReferencesRelatedInformation
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deceased donor liver transplantation,direct oral anticoagulants,transplantation surgery
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