Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study

Sizheng Steven Zhao,Jonas Bovijn,David M Hughes, Tinting Sha,Chao Zeng,Houchen Lyu

Seminars in Arthritis and Rheumatism（2022）

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摘要

We found little evidence of a causal association between genetically predicted vitamin K and OA risk. Larger genetic and interventional studies of vitamin K are required to confirm our findings.

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关键词

Vitamin K,Phylloquinone,Osteoarthritis,Mendelian randomization,Genome-wide association study

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