Structural and functional connectivity abnormalities of the default mode network in patients with Alzheimer's disease and mild cognitive impairment within two independent datasets

Bo Zhou,Xuejiao Dou,Wei Wang,Hongxiang Yao,Feng Feng,Pan Wang,Zhengyi Yang,Ningyu An,Bing Liu,Xi Zhang,Yong Liu

Methods（2022）

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摘要

•Structural and functional connectivity were validated by two datasets.•A reproducible association was found between the PCC and the right hippocampus.•These altered connection indices were correlated with cognitive ability.

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关键词

Alzheimer's disease,Functional MRI,Diffusion-weighted MRI,Default mode network,Connectivity

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