Near-fatal pediatric methemoglobinemia secondary to intentional sodium nitrite ingestion
The American Journal of Emergency Medicine(2022)
摘要
Methemoglobinemia is the result of inappropriate oxidation of hemoglobin iron groups, leading to a failure of oxygen transport and delivery, resulting in a clinical state of refractory hypoxia. Methemoglobin levels above 70% are often considered fatal. Acquired methemoglobinemia can be caused by a variety of substances, including sodium nitrite, a commercially available food preservative and color fixative. This report describes a patient presenting with a methemoglobin level of 83% secondary to intentional sodium nitrite ingestion. The methemoglobin level recorded is amongst some of the highest found in surviving patients.
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关键词
Hypoxia,Methemoglobin,Methemoglobinemia,Methylene blue,Sodium nitrite
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