Environmental enrichment: dissociated effects between physical activity and changing environmental complexity on anxiety and neurogenesis in adult male Balb/C mice.

Physiology & Behavior(2022)

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摘要
•Any change in environmental complexity across time reduces anxiety.•Physical activity without additional housing objects slightly reduces corticosterone.•Cognitive stimuli seem to influence the reduction of corticosterone.•Physical activity increases the number and maturing doublecortin positive cells in the granular cell layer of the dentate gyrus.
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关键词
Adult neurogenesis,Hippocampus,Environmental enrichment,Physical activity,Anxiety,Corticosterone,Doublecortin
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