Effect of Intensive Blood Pressure Reduction for the Prevention of Cognitive Decline and Dementia: A Systematic Review and Meta‐analysis

High blood pressure is a treatable, high risk factor for both cerebrovascular disease and cognitive impairment. Antihypertensive treatment can be viewed therefore as a potential approach to reduce dementia risk. We aimed to examine the effectiveness and safety of intensive, as opposed to standard, blood pressure reduction in adults with hypertension for the primary or secondary prevention of cognitive decline and dementia.