CE/microchip electrophoresis of carbohydrates and glycoconjugates with electrochemical detection

Abstract In this book chapter, the advances in the determination of carbohydrates and glycoconjugates by capillary and microchip electrophoresis with electrochemical detection (CE/ME-ED) will be studied, covering from 2002 to 2019. Amperometric detection, capacitively coupled contactless conductivity detection, and enzyme-based amperometric detection as well as electrochemical derivatization schemes will be critically discussed, showing their advantages and limitations. Furthermore, the most important applications in clinical, pharmaceutical, and food fields will also be highlighted. Future outlooks of CE/ME-ED for carbohydrate determination will also be shown, pointing out those strategies that may improve the sensitivity and selectivity of analytical methods.