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Role of CD36 rs1761667 AA genotype in the expression of inflammatory cytokines and Parkinson’s disease progression: A case-control study in a northern Han Chinese population

Chengqian Li,Binghui Hou,Xiaoyuan Li,Zhengjie Yang,Anmu Xie

Neuroscience Letters（2022）

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Abstract
•The CD36 rs1761667 AA genotype may increase susceptibility to Parkinson’s disease.•The CD36 rs1761667 AA genotype is associated with reduced plasma CD36 levels.•Plasma IL-6/1β and TNF-α levels are elevated in patients with PD and AA/GA carriers.•IL-6/1β and TNF-α levels are risk factors for PD in a northern Han Chinese population.
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Key words
CD36,Parkinson’s disease,Gene polymorphism,Inflammatory cytokines,Microglia,Neuroinflammation
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