Two-Year Tumor Outcomes of a Phase 2B, Randomized, Double-Blind Trial of Avasopasem Manganese (GC4419) Versus Placebo to Reduce Severe Oral Mucositis Owing to Concurrent Radiation Therapy and Cisplatin for Head and Neck Cancer

Carryn M Anderson,Christopher M Lee,Deborah Saunders,Amarinthia E Curtis,Neal E Dunlap,Chaitali Nangia,Arielle S Lee,Philip Kovoor,Voichita Bar-Ad, Abhinand V Pedadda,Jon Holmlund,Matt Downs,Stephen T Sonis

International Journal of Radiation Oncology*Biology*Physics（2022）

引用 6|浏览8

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摘要

Avasopasem does not lead to statistically different tumor control outcomes when used concurrently with cis and RT for head and neck cancer. There was no detectable effect on trismus or xerostomia.

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关键词

avasopasem,head and neck cancer,oral mucositis,radiation therapy,tumor outcomes

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