Synergistic effects of liver fibrosis and sarcopenia on endothelial dysfunction and arterial stiffness in patients with type 2 diabetes

Teruo Jojima,Hidetaka Kurai,Dai Tanuma,Hayato Kajitani,Masato Kase, Yuiko Inoue,Shintaro Sakurai,Toshie Iijima,Takuya Tomaru,Isao Usui,Yoshimasa Aso

IJC Heart & Vasculature（2022）

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摘要

LF and sarcopenia are independently associated with endothelial dysfunction and arterial stiffness in patients with type 2 diabetes. Coexistence of LF and sarcopenia may synergistically lead to vascular damage and thus contribute to the high risk of cardiovascular disease in people with type 2 diabetes.

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关键词

NAFLD,Liver fibrosis,Sarcopenia,Endothelial dysfunction,Reactive hyperemia,Arterial stiffness,Cardio-ankle vascular index,Pulse wave velocity,Cardiovascular disease

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