Effects of 5-aminolevulinic acid on the inflammatory responses and antioxidative capacity in broiler chickens challenged with lipopolysaccharide

Jiang Chen,Huakang Wang,Zhengke Wu, Hongxia Gu,Chong Li,Shaolong Wang,Guohua Liu

animal（2022）

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摘要

•5-ALA supplementation reduced the feed to gain of broilers during days 1–15.•5-ALA supplementation improved the antioxidative capacity of broilers.•5-ALA supplementation attenuated LPS-induced expression of pro-inflammatory cytokines.•5-ALA supplementation promoted the expression of HO-1.•5-ALA exhibited anti-inflammatory effects by inhibiting the TLR4/NF-κB signalling pathway.

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关键词

δ-Aminolevulinic acid,Haem oxygenase-1,Inflammation,Oxidative stress,TLR4/NF-κB

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