Unfolded protein response is involved in the metabolic and apoptotic regulation of oral squamous cell carcinoma
Pathology(2022)
摘要
Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) have been shown to be crucial in the pathogenesis and response to treatment in various cancers. However, such response has not been profiled in oral squamous cell carcinoma (OSCC), the most frequent form of cancer in the head and neck region.
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关键词
OSCC,oral cancer,UPR,ER stress,apoptosis,heat shock protein,DDIT3,SREBP1,SREBF1,CREB3L3
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