Treatment outcomes of standard (high dose) cisplatin and non-standard chemotherapy for locally advanced head and neck cancer.

Muhammad Alamgeer,Andrew Coleman,Lachlan McDowell,Charles Giddings, Adnan Safdar,Elizabeth Sigston, Yang Wang,Ashwin Subramaniam

Cancer reports (Hoboken, N.J.)（2023）

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摘要

We demonstrated similar efficacy of lower dose weekly cisplatin and carboplatin/paclitaxel regimens and better safety profile of weekly cisplatin compared to standard HD cisplatin regimens for LA-HNSCC. Multicenter randomised control trials are required in HD cisplatin-ineligible patients.

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关键词

carboplatin/paclitaxel,cetuximab,cisplatin,locally advanced head and neck cancer,toxicity

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