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Four-year Experience of Liver Transplantation in National Cancer Center of Mongolia

Annals of hepato-biliary-pancreatic surgery/Annals of Hepato-Biliary-Pancreatic surgery(2022)

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摘要
Background: Liver transplantation (LT) is the gold standard treatment for patients with end-stage liver disease.In Mongolia, the main reason for LT is liver cancer and hepatitis B virus, hepatitis c virus-related liver cirrhosis.Liver cancer is by far the leading cancer in Mongolia, contributing almost two-fifths of the total cancer burden.Samsung Medical Center of Korea (SMC) have a big role to set up LT program at National Cancer Center of Mongolia (NCCM) since 2011.During this project doctors and nurses of NCCM were trained for LT several times at SMC. Methods: We just started our liver transplant program in 2018 with our honor partner SMC organ transplant center.We performed 46 liver transplants (living donor LT [LDLT], n=37; deceased donor LT [DDLT], n=9) from January 2018 to February 2022.The aim of this study was to report outcome of this 4-year experience of liver transplantation.Results: Among 46 patients (20 males and 26 females) of overall mean age of 48 who underwent LDLT (all of them right lobe exclude MHV).The postoperative outcomes observed in each LDLT and DDLT recipients were death (21.6% and 11.1%), renal failure (4.3% and 11.1%), postoperative GI tract bleeding (4.3% and 11.1%), liver graft subcapsular hematoma (both 6.6%), and hepatocellular carcinoma recurrence (both 6.7%).In LDLT recipients, the most common posttransplant complications were biliary leakage (both 21.7%) and surgical complication (22.5% and 23.9%) and postoperative bleeding (11.7% and 44.4 %).Conclusions: This report is only based on 46 cases.In order to have long term results, we need to have more operations and experiences for a long time.We have concentrated on our selection criteria choosing LDLT patients.Our long-term purpose is to update economical and effective protocol.
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关键词
Liver Transplantation,Living Donor Liver Transplantation
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