1011-P: School-Day Routines Positively Impact Time in Range for Children with Type 1 Diabetes

The impact of school day routines on glycemic control in children is unclear. We compared continuous glucose monitor (CGM) metrics for youth with type 1 diabetes during weekday school hours (8AM-3PM) between two 4-week periods before and during the COVID-pandemic, when children had transitioned to virtual school. Youth with >70% CGM wear (n=209) were included; 46% male, mean±SD age 10.6±1.5 years, hemoglobin A1c 7.5±0.8%, 64% on insulin pumps. Time in range (TIR, 80-180 mg/dL) was similar during the pandemic (51.6±24.1%) compared to pre-pandemic (50.8±23.3%) . Using random coefficient multilevel linear mixed models, younger age (p=0.025) and pump use (p=0.043) predicted TIR, but not race (p=0.76) , diabetes duration (p=0.07) , body mass index (p=0.54) , or insurance status (p=0.45) . TIR pre- vs. during the pandemic varied significantly by time of day (p<0.001) . With in-person school pre-pandemic, TIR increased over school hours; with virtual school during the pandemic, TIR decreased in the morning and then remained steady (Figure) . Time above range (TAR, >180 mg/dL) had the opposite pattern. These findings suggest that in-person school can contribute to better TIR and lower TAR. Possible explanations include classroom and physical activity routines, plus school nurse support. During virtual school, continued routines are important and interventions to optimize diabetes care in school may benefit glycemic control. Disclosure C.March: None. J.K.Lutz: None. K.Jeong: None. L.M.Siminerio: Advisory Panel; Abbott, Bayer AG, Research Support; Becton, Dickinson and Company, Sanofi. S.D.Rothenberger: None. E.Miller: Other Relationship; Wolters Kluwer Health. I.Libman: Consultant; Novo Nordisk. Funding ISPAD-JDRF Fellowship Award UPMC Children's Hospital of Pittsburgh Cochrane Weber Endowment