Risk Prediction Models for Depression in Community-Dwelling Older Adults

•What is the primary question addressed by this study?Can we reliably identify older individuals at risk for depression?•What is the main finding of this study?Using selected information, the Manto Risk Prediction Models can predict the risk for developing of depression 2 years later with satisfactory accuracy. The streamlined Manto Risk Prediction Model is available for free public use through a web-based risk calculator (https://manto.unife.it/).•What is the meaning of the finding?Estimating an individual's risk for developing late-life depression allows to target prevention strategies at an individual and a population-level.