Corroles As Precursors of Porous Organic Polymers (POPs) and Molecularly Imprinted Polymers (MIPs) - Application to the Detection of CO and the Decontamination of Chemical Nerve Agents

Detection of carbon monoxide (CO) at few ppm levels is a critical point for quality control of domestic and industrial environment. CO is responsible for thousands of intoxications and hundreds of deaths per year in the world. Moreover, CO is a residual gas found in the industrial dihydrogen used for Proton Exchange Membrane fuel cell, and deactivates the fuel cell prematurely. Corroles have been largely used in sensing applications.[1] Cobalt corroles display high binding affinity for carbon monoxide even in the presence of nitrogen and dioxygen.[2] The affinity of the Co(III) metallocorroles for CO is directly correlated with the Lewis acid character of the metal center. The electrochemistry and spectro-electrochemistry properties have been studied. We have shown that structural modifications on the aromatic ring have a direct influence on the reactivity of the metal complex. We have recently obtained very low CO detection level (ppm) using SAW devices functionalized by cobalt corrole deposited as a film on a silica or a gold surface.[3] Our previous work on the synthesis of porous sol-gel materials functionalized by cobalt corroles gave us encouraging results for CO sorption and detection and prompted us to prepare new porous structured materials functionalized by corrole complexes for gas detection applications. Among all the methods of synthesis of porous architectures, organic materials belonging to the POP (Porous Organic Polymer) family are an appealing and original approach in this research field.[4] The synthesis of new POPs functionalized by cobalt corroles (Fig. 1) will be reported. Their selective sorption properties for CO over N2, O2 and CO2 will be also presented. Preliminary results concerning the design of Molecularly Imprinted Polymers (MIPS) as enzyme mimics for the decontamination of a broad spectrum of pesticides and chemical warfare agents will be also reported. Authors would like to acknowledge the ANR program (MIPEnz-Decontam, 20-CE39-0016-01), the FEDER and the “Région Bourgogne” for financial support (ISITE CO2DECIN) REFERENCES: [1] Di Natale, C.; Gros, C. P.; Paolesse, R., Chem. Soc. Rev. 2022, 000;[2] J.-M. Barbe, G. Canard, S. Brandès, F. Jerôme, G. Dubois, R. Guilard, Dalton Trans. 2004, 1208-1214; [3] Vanotti, M.; Poisson, S.; Soumann, V.; Quesneau, V.; Brandes, S.; Desbois, N.; Yang, J.; Andre, L.; Gros, C. P.; Blondeau-Patissier, V., Sensors and Actuators B: Chemical 2021, (332), 129507. [4] S. Brandès, V. Quesneau, O. Fonquernie, N. Desbois, V. Blondeau-Patissier, C. P. Gros, Dalton Trans. 2019, 48, 11651-11662 (Front Cover). Figure 1