Efficient Detection of Glucose by Graphene-Based Non-Enzymatic Sensing Material Based on Carbon Dot

Diabetes is one of the global chronic diseases, which is mainly caused by the abnormal increase of blood sugar level. Therefore, it is particularly important to monitor glucose in real time. In this work, based on the principle that phenylboronic acid can react with diol rapidly and reversibly in aqueous medium, phenylboronic acid functionalized reduced graphene oxide (rGO-PBA) and polyhydroxy modified carbon spot fluorescent probe (CD1) were designed for detecting important glucose molecules. Among them, reduced graphene oxide (rGO) has high specific surface area and strong fluorescence quenching performance. When CD1 is close to the surface of rGO-PBA, the fluorescence of carbon dots was quenched. With the addition of glucose, the fluorescence of carbon dots increased continuously. The detection of small molecule glucose can be realized quickly and sensitively by using the "on" and "off" strategies of fluorescence.