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Datasets for a simulated family-based exome-sequencing study

Data in Brief(2022)

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摘要
We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected family members. We provide a brief overview of the simulation steps and links to the associated software scripts. The resulting data are useful to identify genomic patterns and disease inheritance in families with multiple disease-affected members.
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关键词
Family studies,Exome sequencing,Lymphoid cancer,Ascertained pedigrees
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