Comprehensive orthodontic treatment for Silver-Russell syndrome patient with large overjet and overbite

Purpose Silver-Russell syndrome (SRS) is a congenital malformation syndrome with a growth disorder characterized by intrauterine and postnatal growth retardation leading to short stature, body asymmetry, characteristic triangular facies and several other anomalies. Materials and methods This report describes comprehensive orthodontic treatment of a girl aged 11 years and 1 month with SRS. She showed skeletal class II with asymmetrical facial profile, constricted upper and lower arches, crowding and large overjet and overbite. Results In the first phase of orthodontic treatment, the constricted arches, large overjet and skeletal class II showed improvement by functional appliance with expansion screw. At the age of 13 years and 7 months, second phase orthodontic treatment was started in order to improve severe crowding, large overjet and overbite by preadjusted edgewise appliance and temporary anchorage devices with four bicuspids extraction. Favourable facial profile and occlusion were achieved at the end of active treatment. Conclusion Long-term follow-up is also essential in order to assess long-term stability of this treatment.