Gold Nanoparticles and Graphene Oxide Based Low Cost Glucose Sensing Technique

Diabetes is a chronic metabolic disease characterized by abnormally high blood glucose (or blood sugar) levels. Over time, diabetes can cause serious damage to the heart, blood vessels, eyes, kidneys, and nerves. As a result, this work proposes a low-cost glucose sensing method based on graphene oxide (GO) and gold nanoparticles (AuNPs). GO is synthesized from laboratory-grade graphite powder and is used to enhance glucose solution detection via gold nanoparticles (AuNPs). A modified Hummer's method is used to prepare GO, and the Turkevich method is used to synthesize AuNPs in this process. X-ray diffraction (XRD) is used to analyze the structure, whereas Fourier transform infrared spectroscopy (FTIR) is used to study the functional groups attached to the GO. We also used transmission electron microscopy (HR-TEM) to characterize the morphology of GO and AuNPs. A UV–visible spectrophotometer is used to obtain the absorption spectra of synthesized samples. The surface plasmon peak indicates that the sensor has a linear range of glucose concentrations ranging from 1 to 9 mM. With the addition of GO, the sensing performance has been improved.