A Report of Haploidentical Allogeneic Haematopoietic Stem Cell Transplantation for Inherited Bone Marrow Failure in Sri Lanka
British Journal of Haematology(2021)
摘要
Abstract Bone marrow failure (BMF) in children can be idiopathic (70-80%) or inherited. Haematopoietic stem cell transplantation (HSCT) is the only cure for both causes. Allogeneic HSCT requires a suitable donor. Many children will not have a HLA matched sibling or unrelated donor. A haploidentical donor is available for all children as eaazch parent will have at minimum a 50% HLA match. This report of a 7-year old girl with BMF treated with a haplo-HSCT, the first in Sri Lanka, highlights the importance of developing a haploidentical HSCT programme as a potential cure for a disease with a dismal outcome.
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关键词
Hematopoietic Stem Cell Transplantation
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