Suppressed Cellular Senescence Mediated by T-box3 in Aged Gastric Epithelial Cells may Contribute to Aging-related Carcinogenesis.

Akio Takeuchi,Naoki Asano,Akira Imatani,Masashi Saito,Xiaoyi Jin,Masahiro Saito,Takeshi Kanno,Waku Hatta,Kaname Uno,Tomoyuki Koike,Atsushi Masamune

Cancer research communications（2022）

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摘要

This work provides an insight into the mechanism involved in aging-related gastric carcinogenesis through studies utilizing organoids established from young and aged murine stomachs.

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关键词

aged gastric epithelial cells,cellular senescence,epithelial cells,t-box,aging-related

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