Impact of Rituximab and Corticosteroids on Late Cytopenias Post-Chimeric Antigen Receptor T Cell Therapy
Transplantation and Cellular Therapy(2022)
摘要
•Cytopenias represent significant adverse events of chimeric antigen receptor (CAR) T cell therapy.•Increased exposure to rituximab pre-CAR T cell therapy is associated with persistent anemia and thrombocytopenia post-CAR T cell therapy.•An increased number of prior lines of therapy is associated with persistent lymphopenia and anemia post-CAR T cell therapy.
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关键词
Chimeric antigen receptor T cell therapy,Rituximab,Lymphoma,Cytopenia
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