Frequent detection of functional hyposplenism via assessment of pitted erythrocytes in patients with advanced liver cirrhosis.

Malte H Wehmeyer, Harsha Sekhri, Raluca Wroblewski,Antonio Galante,Thomas Meyer,Ansgar W Lohse,Julian Schulze Zur Wiesch

PloS one（2022）

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摘要

A quarter of patients with liver cirrhosis and almost 50% of patients with Child C cirrhosis have functional hyposplenism. Functional hyposplenism is associated with poor liver function and the degree of portal hypertension, which is characterized by higher liver stiffness measurements in transient elastography.

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