Inhibition of platelet aggregation by activation of platelet intermediate conductance Ca2+‐activated potassium channels

Valentina Back,Amir Asgari,Aleksandra Franczak,Max Saito, Diego Castaneda Zaragoza,Shaun L Sandow,Frances Plane,Paul Jurasz

Journal of Thrombosis and Haemostasis（2022）

引用 2|浏览9

暂无评分

摘要

Platelet IK channel activation inhibits aggregation by reducing calcium-signaling and granule secretion, but not by enhancing platelet NO generation. IK channels may be novel targets for the development of antiplatelet drugs that limit atherothrombosis, but not coagulation.

查看译文

关键词

intermediate conductance Ca2+‐activated K+ channels,nitric oxide,platelet aggregation,platelets,thrombosis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要