Clinical and genomic characterization of interval colorectal cancer in three prospective cohorts

Keming Yang,Yin Cao,Yang Liu,Carino Gurjao,Chuan-Guo Guo,Chun-Han Lo,Xiaoyu Zong,David A. Drew, Connor M. Geraghty,Elizabeth Prezioso, Matthew Moore,Craig R. Williams,Tom Riley,Melissa Saul,Brenda Diergaarde,Shuji Ogino,Marios Giannakis,Adam Bass,Robert E. Schoen,Andrew Chan

Gastroenterology（2022）

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摘要

Colorectal cancers diagnosed between screening examinations (interval cancers) had significantly increased risk of death than screen detected cancers, although no significant molecular differences were observed between them at a whole exome sequencing level.

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关键词

colonoscopy,interval colorectal cancer,screening,whole exome sequencing

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